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what is FPIES?

What is FPIES? 

Food Protein-Induced Enterocolitis Syndrome (FPIES) is sometimes referred to as a delayed food allergy. It is a severe condition causing vomiting and diarrhea/constipation. In some cases, symptoms can progress to dehydration and shock brought on by low blood pressure and poor blood circulation.

Much like other food allergies, FPIES allergic reactions are triggered by ingesting a particular food. Although any food can be a trigger, most common culprits include milk, soya and grains.

Most children with FPIES have only one or two food triggers, but it is possible to have FPIES reactions to multiple foods. FPIES often develops in infancy, usually when a baby is introduced to solid food or formula.

What is a typical FPIES reaction? 

As with all things, each child is different, and the range of severity and duration of symptoms may vary from reaction. Unlike traditional IgE-mediated allergies, FPIES reactions do not manifest with itching, swelling, coughing, hives or wheezing, etc.

Symptoms typically only involve the gastrointestinal system, and other body organs are not involved. FPIES reactions almost always being with a delayed onset vomiting (usually two hours after ingestion, sometimes as late as eight hours afterward). Symptoms can range from mild (an increase in reflux and several days of runny stools) to life-threatening (shock).

In severe cases, after repeatedly vomiting, children often begin to vomit bile. Commonly diarrhea follows and can last up to several days.

In the worst reactions (About 20% of the time) the child has such severe vomiting and diarrhea that she rapidly becomes seriously dehydrated and may go into shock.

International FPIES Foundation

For more information on FPIES, please visit the FPIES foundation website. Everything you need to know is on their website.